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Recipients of the J&J vaccine should receive their second dose as soon as it is available, experts say



“J&J is a very good vaccine. I also think it’s probably a two-shot vaccine,” said Dr. Ashish Jha, dean of Brown University School of Public Health. “It is very urgent that people get this second shot fairly quickly.

“It’s probably not enough. And everyone who has had one needs a second two months after the first. If they do, they’ll get full protection,” he said.

The advisory committee of the US Food and Drug Administration recommended Friday that all adults who received a single dose of J&J should receive a second vaccine at least two months after the first dose.
Thursday, the same committee authorization for use of supported emergency for reinforcement firing of the Modern Covid-19 vaccine after six months, but not for everyone. Modern recipients over the age of 65 and adults who are at risk for serious illness or who work or live in a place that presents them with a higher risk of complications or serious illness may be eligible for the 50 microgram boost, which is half the size of the main two-dose series.

But as for the J&J vaccine, which was launched as a single-dose regimen, experts point to a combination of diminishing immunity and the spread of the Delta variant as the main drivers of a second dose.

A study published Thursday reported a sharp decline in the effectiveness of the infection vaccine in August this year, especially for people who received the J&J vaccine.

The researchers found that among more than 600,000 veterans, protection against the J&J vaccine fell from 88% in March to 3% in August. Meanwhile, Moderna’s vaccine protection against infection fell from 64% to 64%, and Pfizer decreased to 50% from 91% during that same time period.

“I think anyone who has gotten a dose of the Johnson & Johnson vaccine can benefit from a second dose of a Johnson & Johnson vaccine,” said Dr. Paul Offit, a member of the FDA’s Advisory Committee on Vaccines and related biological products.

Offit told CNN’s Jake Tapper that he believes the J&J vaccine would probably have been a two-dose series if the country hadn’t been facing the urgency of the pandemic.

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Approximately 15 million Americans have received the J&J vaccine, according to the US Centers for Disease Control and Prevention, and almost 91% of them received it more than two months ago.

The FDA will consider the committee’s latest recommendations on J&J and Moderna vaccines, and if an emergency use authorization is granted, the CDC will decide who is eligible for the doses.

The third dose of Pfizer was approved last month for people over 65 and people over 18 at risk of serious illness or living or working in a situation that puts them at greater risk for complications or serious illness.

CDC officials say the “clear need” to mix and increase firearms is high

As more drivers are expected to become available, public health officials and experts have been considering a combined approach.

Dr. Amanda Cohn, who is the medical chief of the CDC’s National Center for Vaccination and Respiratory Diseases, said Friday that the guidelines on mixing and combining booster shots would give flexibility.

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“I think from a public health perspective there’s a clear need in some situations for people to get a different vaccine,” Cohn said, noting, for example, that J&J recipients may not have access to a second dose. of the same vaccine. “So if there is no language allowed on the FDA fact sheets or U.S. authorization, then those people are left behind,” he said.

Already, about 9.7 million people have received an additional dose or a booster dose, According to the CDC.

Cohn’s statements come when FDA vaccine advisers were asked to discuss data showing that it is safe to mix the three authorized Covid-19 vaccines (Modern, Pfizer and J&J) when booster injections are given.

The National Institutes of Health presented early information from an ongoing study that showed that it didn’t matter what vaccine the first people got and what booster they got: it was safe to mix booster and boost the immune response. In addition, blend boosters also provided a good response to the Delta variant.

Cohn also noted that there is a rare side effect of blood clotting known as thrombosis with thrombocytopenia syndrome or TTS, which is more common in young women and is associated with the J&J vaccine.

A health worker fills a syringe with the Pfizer Covid-19 vaccine at Jackson Memorial Hospital on October 5, 2021, in Miami.

Vaccine mandates continue to hold up

Experts, including U.S. Surgeon General Vivek Murthy, have said vaccine mandates are working to increase the number of vaccines. But this is not without some reaction.

Nationally, the U.S. has completely vaccinated more than 56 percent of its total population, but health and government officials have been pushing to increase those numbers.

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In Seattle, however, the police department’s deadline is Monday, and about 10 percent of employees have yet to file vaccination evidence.

Data released by the mayor shows that 82% of Seattle police department staff are vaccinated. The remaining 8% ask for religious or medical exemptions, according to the police department.

“We’ve seen increases in submissions over the past week,” Mayor Jenny Durkan’s chief of staff, Stephanie Formas, said in an email to CNN. “COVID-19 is currently the leading cause of death for our first officers and, throughout the pandemic, we have seen dozens of firefighters and officers exposed with some hospitalized.”

Also in Washington state, Boeing Everett Factory employees gathered Friday at the facility’s facility in Everett to protest the company’s vaccine mandate that was announced in early this week. Workers must be vaccinated before December 8, unless they provide “reasonable accommodation” derived from a disability or religious beliefs.

“Boeing is committed to maintaining a safe work environment for our employees and advancing the health and safety of our global workforce is critical to our values ​​and is a core priority every day,” Boeing said in a statement Friday. on CNN after the protest.

CNN’s Maggie Fox, Jen Christensen, Amy Simonson and Whitney Wild contributed to this report.